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An experimental procedure was developed to measure the Wru Grand Slam T Shirt 2019 stress-free equilibrium volume of intact lobes from the lung of the dog. The procedure eliminates body, gravitational, interfacial, and externally applied forces to study the contribution of the tissue forces. The equilibrium gas volume was found to be times the tissue volume and was independent of the volume history. This is smaller than the minimal air volume found by others and about one half the functional residual capacity volume.
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The lung was found able to resist compressive loading implying a “finite buckling load” for the alveolar septa. A simple calculation shows the length-to-thickness ratio to be at the stress-free equilibrium volume and incorporation of these data into a mathematical modeling framework with computed output visualized as the tissue partial pressure of distribution across a biopsy sample. Worked examples are provided using muscle samples from experiments involving rats and humans.
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Progress in quantitative morphometry and analytical modeling has tended to develop independently. Real diagnostic power lies in harnessing both disciplines within one user-friendly package. We present a semiautomated, high-throughput tool for determining muscle phenotype from biopsy material, which also provides anatomically relevant input to quantify tissue oxygenation, in a coherent package not previously available to nonspecialist investigators.
Scott and colleagues make a compelling argument that birds are far superior to mammals at adapting and thriving in hypoxic environments, both at rest and during exercise. While their argument is supported by comparisons between birds and terrestrial mammals, it ignores marine mammals. Marine Wru Grand Slam T Shirt 2019 mammals such as seals are routinely exposed to and tolerate long bouts of hypoxia during breath-hold diving. For example, elephant seals may dive to depths of nearly 1,600 m and occasionally remain submerged for.