While it is unknown what effect, if any, intermittent walking would have on MCA diameter, an increased diameter would translate to a decrease in velocity and vice versa for a decreased diameter, assuming constant flow. data were obtained under quiet resting conditions. Furthermore, the impact of LGBTQ BBQ Shirt active breaks on carbon dioxide at the time of measurement seems unlikely, since there was required for ratio normalization, where one number is divided by another.
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These differences between studies likely represented a different stimulus to a range of mechanisms responsible for regulating cerebral blood flow data were statistically adjusted for contemporaneous blood pressure in regression analyses, and it is therefore unlikely that our cerebrovascular findings are primarily related to underlying changes in driving pressures. This type of correction avoids the need to meet stringent assumptions.
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While our study was not designed to address the mechanisms responsible for effects on MCAv, several possibilities may exist. Brain blood flow is controlled by multiple redundant and integrative mechanisms and is highly protected by local and reflex pathways. Although differences existed between conditions in blood pressure responses. A further mechanism that controls cerebral blood flow is the partial pressure of carbon dioxide in the circulating blood.
The authors demonstrated an increase in MCAv pre to post a 4-h period involving breaks in sitting, compared with prolonged uninterrupted sitting. Although we observed an attenuation in average MCAv following intermittent walking, this was after an antecedent bout of morning exercise in a population of older LGBTQ BBQ Shirt overweight and obese adults (mean age 70 yr), compared with walking breaks alone in a younger healthy population (mean age 36 yr) in the study by Carter et al.