A strength of this study is the well-controlled randomized crossover design, which controls for person-specific factors and affords smaller sample sizes. Trial conditions were also standardized for potential confounders such as diet, physical activity, medications, and baseline values. However, direct Belles Smokin BBQ Shirt measures of intracranial diameters are not currently possible using ultrasound and velocity is therefore relied on as a surrogate measure of flow.
Belles Smokin BBQ Shirt is available in all styles
This is less of an issue for within-subject experimental designs because blood flow changes are heavily dependent on velocity change. However, we cannot rule out distinct effects on artery diameter responses that went undetected. Future experiments utilizing electroencephalography or near-infrared spectroscopy may help to better understand complementary and temporal patterns of change in cerebrovascular function in the future.
Belles Smokin BBQ Shirt, Hoodie and Sweater designed by Beauty T-shirts
Furthermore, positron emission tomography and MRI would provide information on the spatial distribution of brain blood flow. In addition, it is unknown whether the changes observed simply represent a local effect on the brain vessels per se or an impact on cerebral activation that subsequently affected brain blood vessels. Future studies, perhaps including functional MRI, may be utilized to test how brain networks are affected by the combination of exercise and breaks in sitting.
This is relevant since metabolic activity in the brain is known to also affect regional cerebral blood flow. Finally, given expected regional differences in cerebral blood flow, our findings are not generalizable to the posterior circulation. There are also some limitations to our study. The experiment was designed as a Belles Smokin BBQ Shirt superiority trial, and we did not include a fourth condition involving walking breaks alone. This was due to general acceptance.